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Quiz of the Week

July 17, 2012

Photo courtesy of Saurabh S. Chiwane, MD

A 9-month-old girl presented for a well-child check. She was in the 75th percentile for weight and 50th percentile for length. She had excessive skin folds over her arms and legs and bilateral epicanthic folds. She was developmentally appropriate and had no other congenital anomalies. The rest of the physical examination findings were normal.

What are these circumferential symmetric skin creases called? Does this finding portend a benign or ominous prognosis?

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by jaume querol | July 20, 2012 10:34 PM EDT

Syndrome of multiple benign skin folds in the limbs (Michelin tire baby syndrome).
The pattern of skin creases tends to be symmetrical,temporary and does not adversely affect the patient's health.
There are reports that presented:cleft palate,craniofacial anomalies,hypoplastic scrotum and hernias,joint hypermovilitydevelopmental delay,psychomotor retardation,epilepsy.hypertrichosis and smoth muscle hamartoma.

Variability in the Michelin tire syndrome. A child with multiple anomalies, smooth muscle hamartoma, and familial paracentric inversion of chromosome 7q.Journal of the American Academy of Dermatology
Volume 28, Issue 2 , Pages 364-370, February 1993

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